At some point in the next year, SecState Clinton will resign in protest over something or another and announce that she’s running against President Obama.

Five Six Reasons:  James Carville has come out at least twice with great ferocity against President Obama’s inaction on the BP oil spill.  President Bill Clinton is openly backing a non-Obama candidate in a local election.  SecState Clinton doesn’t strike me as the patient sort.  Two years out and the Republicans don’t have a recognizable candidate to rally around.  I’ve heard people from both sides of the political spectrum express the sentiment, “ANYbody but Obama!”  Hillary has got to be pissed off that President Obama is giving her job to everyone, including NASA.